The relationship between art and entrepreneurship, as two seemingly different fields, has become an attractive topic for researchers in recent years. On the one hand, art is recognized as a rich source of creativity, innovation and critical thinking. On the other hand, entrepreneurship is considered as the driving engine of economic growth and creating new job opportunities. This research has been done with the aim of investigating the interaction between art and entrepreneurship and identifying the opportunities and challenges in this field. In this research, a combined method including literature study, interviews with artistic entrepreneurs and case analysis have been used. The literature related to art, entrepreneurship and creative economy has been carefully reviewed and compared with the findings from interviews and case studies. The findings of this research show that art can play an important role in the development of entrepreneurship. By using their creativity and artistic skills, artists are able to create innovative products and services that meet the needs of the market. Also, art can be used as a powerful tool for branding and marketing products and services. On the other hand, entrepreneurship can also help artists to turn their ideas into reality and earn money through the sale of works of art. The relationship between art and entrepreneurship has a high potential for creating added value and economic development. By supporting entrepreneurial artists and creating suitable infrastructure, we can help the growth of the creative economy and create employment in this field. This research shows that art and entrepreneurship are not only two separate fields, but can act as complements to each other and help the sustainable development of societies.