The main purpose of this study is to investigate the impact of innovation in entrepreneurship on customer value creation behaviors through the mediating role of customer interaction. The statistical participants of this research is the customers of online sales sites. Therefore, 384 people were determined as the sample size. The questionnaires were distributed randomly. The article of Yen et al. (2020) was used to design the questionnaire. Structural equation modeling and AMOS software were used to analyze the questionnaires. The analysis of information collected from research questionnaires illustrated that innovation in entrepreneurship has a positive and significant effect on customer participation behaviors. Innovation in entrepreneurship has a positive and significant effect on customer citizenship behaviors. Customer interaction has a positive and significant effect on customer participation behaviors. Customer interaction has a positive and significant effect on customer citizenship behaviors. Customer interaction has a mediating and positive role in the relationship between innovation in entrepreneurship and customer participation behaviors. Customer interaction has a mediating and positive role in the relationship between innovation and customer citizenship behaviors.