Abstract
Background: Polycystic ovary syndrome (PCOS) is a common endocrine–metabolic disorder that affects reproductive health, insulin sensitivity, and systemic inflammatory processes. Naturopathic interventions—including nutritional therapies, herbal medicine, targeted supplementation, and lifestyle modification—have gained increasing interest as complementary strategies to address the multifactorial nature of PCOS.
Objective: This review synthesizes evidence published between 2015 and 2025 on the effectiveness of key naturopathic interventions—such as inositol, berberine, vitamin D, omega-3 fatty acids, and lifestyle modification—in improving metabolic, hormonal, and clinical outcomes in women with PCOS.
Methods: A structured literature search was conducted in PubMed, Scopus, and Google Scholar. Fifteen eligible studies, including clinical trials and systematic reviews, were selected and qualitatively analyzed based on relevance to PCOS-related endocrine and metabolic outcomes.
Results: The reviewed interventions demonstrated potential benefits in reducing insulin resistance, lowering androgen levels, improving lipid profiles, decreasing inflammation, and enhancing ovulatory function. Inositol and berberine, in particular, showed the most consistent metabolic improvements across the included studies.
Conclusion: Naturopathic interventions represent promising complementary options for managing PCOS, offering improvements in both metabolic and reproductive parameters. However, further high-quality randomized trials are required to determine optimal dosing, treatment duration, and comparative efficacy among different therapies.
